For organizations or individuals with specific needs, Microsoft and third-party vendors offer solutions like Microsoft Application Virtualization (App-V) that can virtualize applications, making them accessible in a more portable manner. However, these solutions are typically targeted at enterprise environments.
Microsoft does not offer an official "portable" version of Office 365 (now Microsoft 365 ) that can be run from a USB drive without installation. Official deployment methods require a full local installation or access via a web browser. Official Deployment vs. "Portable" Concepts microsoft office 365 download center portable
For legitimate study or use, refer to the Office Deployment Tool documentation . For security research, look for papers on "Malware propagation through software cracks" to understand the risks of unofficial portable software. For security research, look for papers on "Malware
However, a specific search query has been gaining traction among IT professionals and road warriors: For security research